In 1971, he was consecrated Metropolitan of Thessalonica, taking up additionally the pastorship of Eastern Macedonia and Thrace. As Metropolitan of Thessalonica he dedicated all his energies to the organization of his Diocese until 1986, when he was elected Archbishop of Athens and First-Hierarch of the Genuine Orthodox Church of Greece—the office which he held until 6 September 2010 (o.s.) when he reposed in the Lord after divine liturgy on the feast of the miracle of the Archangel Michael at Chonai.
It was during his pastorship that the Genuine Orthodox Church of Greece was formally recognized by the Hellenic Republic, providing a legal framework for the preservation of Church properties and the recognition of the sacraments of the Genuine Orthodox Christians in the municipal registries—an act essential for the full participation of the Genuine Orthodox Christians in the civic life of Greece. Weathering many storms, he succeeded in the much-desired purification of the clergy of foreign and alien elements, which had found their way in the struggle of the Genuine Orthodox Church, renewing the body of the clergy with new episcopal consecrations in 1998, 1999, and 2000, and bringing previously separated brothers into the unity of the Church. It was his grace-filled, steady-handed piloting that provided for the peaceful stability, unity, and growth of the Church of the Genuine Orthodox Christians in Greece and abroad during the last decade of his reign. Archbishop Chrysostomos II will be remembered as a man of deep prayer and a clear-sighted and unfaltering helmsman that led the Church through times of storm and crisis and emerged leaving for his beloved Church a firm and steady foundation in Christ.
On 8 June 1998 Archbishop Chrysostomos II was received by Constantinos Stephanopoulos, the President of the Hellenic Republic, becoming the first Archbishop of the Genuine Orthodox Christians to be received by a Greek Head of State.
May his memory be eternal!